Because tramadol is an opioid, it stands to reason that it would share similar overdose symptoms with its peers in pill form. Moreover, tramadol puts all recreational users at risk of having a seizure — a side effect that increases in probability as more and more is taken. Beyond seizures, overdose symptoms for this medication include:

Respiratory depression
Shallow or absent breath
Weakness or lethargy
Cold, clammy or discolored skin
Dizziness when standing
Pinpoint pupils
Unconsciousness or coma
Irregular heartbeat
Nausea and vomiting
Muscle rigidity

Recognizing these tramadol overdose symptoms is critical in life-threatening situations. Any overdose in which respiration is impacted has the potential to create permanent impairment. With tramadol overdoses in particular, brain damage may occur if not enough oxygenated blood reaches the central nervous system in a timely manner. As such, no opioid overdose symptom should be discounted; obtain medical treatment for yourself or others straightaway.
Tramadol Overdose Amount
How much tramadol does it take to overdose? It really depends solely on the person in question. First, what is considered a generally safe amount? Doctors recommend that patients take no more than 100 mg of tramadol when starting out. This amount may be increased as tolerances do. However, between 300 and 450 milligrams a day appears to be the cap for the medication.

Somewhere between 2 and 8 grams will produce a deadly tramadol overdose response. Tramadol can create toxic side effects far before this, though they aren’t considered part of an overdose. One may experience hazardous effects of the drug at as low as 500 mg — seizures included. Mixing other opioids, sedatives, or alcohol multiples the chance of overdose at smaller milligram quantities. For this reason, physicians recommend that these substances never be combined.

Several potentially fatal consequences may occur if a dosage level constituting an overdose is reached. Asymmetrical heart rhythms may lead to cardiac arrest or even pulmonary edema. Additionally, liver failure is a possibility.
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